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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf48
All Species:
18.18
Human Site:
S466
Identified Species:
40
UniProt:
Q9NWS1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWS1
NP_060385.2
579
65081
S466
L
Y
M
E
N
D
L
S
E
G
V
N
P
S
V
Chimpanzee
Pan troglodytes
XP_509318
760
85084
S647
L
Y
M
E
N
D
L
S
E
G
V
N
P
S
V
Rhesus Macaque
Macaca mulatta
XP_001085518
579
65125
S466
L
H
M
E
N
D
L
S
E
G
V
N
S
S
V
Dog
Lupus familis
XP_855025
579
65071
S466
L
H
V
E
N
D
F
S
E
G
V
N
S
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6IRT3
573
64087
E464
H
L
E
D
D
V
S
E
G
A
Q
S
S
V
G
Rat
Rattus norvegicus
Q9EQ10
573
63884
S464
L
R
L
E
N
D
V
S
E
G
A
Q
P
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507285
579
64417
F466
L
T
L
Q
S
G
W
F
K
G
V
N
S
T
V
Chicken
Gallus gallus
Q5ZKL9
580
65236
H464
P
A
P
K
Q
H
L
H
G
K
Y
F
T
E
G
Frog
Xenopus laevis
Q32N66
567
63030
P461
H
P
A
P
K
I
V
P
V
L
C
F
D
E
E
Zebra Danio
Brachydanio rerio
Q1RMA6
568
62451
S455
H
P
A
P
K
K
A
S
S
E
S
D
N
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178396
861
96268
T656
P
L
V
K
G
Q
Q
T
L
N
C
F
F
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
94.4
82.3
N.A.
69.2
68.7
N.A.
63.2
54.4
50
39.3
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
75.5
96.7
90.6
N.A.
81.3
80.6
N.A.
78.4
72
64.5
56.6
N.A.
N.A.
N.A.
N.A.
37.5
P-Site Identity:
100
100
86.6
73.3
N.A.
0
66.6
N.A.
33.3
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
20
80
N.A.
66.6
13.3
6.6
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
0
0
0
10
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% C
% Asp:
0
0
0
10
10
46
0
0
0
0
0
10
10
0
0
% D
% Glu:
0
0
10
46
0
0
0
10
46
10
0
0
0
19
10
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
0
28
10
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
19
55
0
0
0
10
28
% G
% His:
28
19
0
0
0
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
19
19
10
0
0
10
10
0
0
0
0
0
% K
% Leu:
55
19
19
0
0
0
37
0
10
10
0
0
0
0
0
% L
% Met:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
46
0
0
0
0
10
0
46
10
0
0
% N
% Pro:
19
19
10
19
0
0
0
10
0
0
0
0
28
0
0
% P
% Gln:
0
0
0
10
10
10
10
0
0
0
10
10
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
10
0
10
55
10
0
10
10
37
46
0
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
0
0
10
10
0
% T
% Val:
0
0
19
0
0
10
19
0
10
0
46
0
0
10
55
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _